武学前沿策略性一次性技术采购是避免供应商依赖的关键

　　研究人员表示，供应商依赖是制药公司的一个潜在陷阱，对于生物工艺技术采购的策略方法至关重要。一次性技术领域的竞争非常激烈。为了获得优势，供应商试图通过使用定制操作系统等方式，，或者采用仅可以使用他们提供的特定试剂的设计，来使得他们的平台与众不同。
　　Supplier dependency is a potential pitfall for drug companies, according to researchers who say a strategic approach to bioprocess technology sourcing is vital. Competition in the single-use technology sector is fierce. To gain an edge, suppliers try to differentiate their platforms using, for example, bespoke operating systems or by designing them to only work with specific reagents they also supply.
　　瑞士西部技术大学的Diego Schmidhalter博士说，虽然这提供了更多的选择，但它同时可能也是一个挑战，他说：＂供应商寻求开发独特的销售政策和差异化，对于用户来说则更乐意标准化。大量独特的设计阻碍了供应链替补方案的产生，这是一个在新冠病毒大流行期间突显出来的问题，并解释了许多制药公司因受供应商的原因暂时停产的情况。＂
　　While this creates choice, it can be a challenge, according to Diego Schmidhalter, PhD, from the Technical University of Western Switzerland, who says, ＂Suppliers seek to develop a unique selling proposition and differentiation, while users welcome standardization. The large number of different designs prevents the development of second supply options, which is an issue that became apparent during the COVID-19 pandemic and explains why many drug firms impacted by suppliers temporarily halted production.＂
　　竞争
　　此外，科技行业的竞争在以多种方式影响着价格，Schmidhalter博士补充说，＂开发多种不同的解决方案服务用于同一目的但购买量小，而不是大量订购标准设计的产品，这无疑会推高成本。＂
　　In addition, tech sector competition impacts prices in a variety of ways, Schmidhalter says, adding, ＂The development of multiple solutions serving the same purpose with low purchase volume, rather than a few standard designs ordered at large quantity, drives cost.＂
　　对于其他类型的技术，选择更有限，销量更高。然而，Schmidhalter博士说，缺乏竞争也推高了价格。
　　For other types of technology, choice is more limited, and sales volumes are higher. However, here the lack of competition also increases prices, Schmidhalter says.
　　＂一些供应商主导了特定设备解决方案的市场，例如生物反应器、层析系统或高达2000L规模的切向流过滤装置等。导致该领域缺乏竞争。＂
　　＂A few suppliers dominate the market for specific equipment solutions such as bioreactors, chromatography systems, or tangential flow filtration skids up to the 2000 L scale. There is a lack of competition.＂
　　还有其他原因导致使用一次性系统的制药公司过度依赖供应商。
　　And there are other reasons why drug companies that use single-use systems can become overly reliant on suppliers.
　　Schmidhalter博士说：＂一些一次性设备带有无法在其他地方购买的特定耗材，＂他补充说，＂即使只是缺乏很简单的一些一次性组件，也会导致在供应短缺时使生产面临风险。
　　＂Some single-use equipment comes with specific consumables which cannot be purchased elsewhere,＂ Schmidhalter says, adding ＂even a lack of simple single-use assemblies, can put manufacturing at risk in times of supply shortage.
　　＂此外，有时用户会要求对设备进行额外定制，这可能导致在设备上只能使用定制的一次性组件，从而使自己陷入锁定状态。＂
　　＂In addition, sometimes users maneuver themselves into a lock-in situation, by requesting extra customization of equipment, which may demand customized single-use assemblies to be used on the equipment.＂
　　为了尝试降低对供应商的依赖风险，Schmidhalter博士及其同事在10月发表的一篇研究论文中概述了他们所说的管理一次性技术的策略方法。
　　To try and reduce the risk of supplier dependency, Schmidhalter and colleagues outlined what they describe as a strategic approach to the management of single-use technology in a research paper published in October.
　　＂我们建议，策略应侧重于设备标准化、通过定义标准组件实现一次性组件的标准化、以及耗材的设计规则，＂他们指出。＂我们还建议在公司内引入一种通用方法来定义一次性组件，开发并在全公司范围内引入工具，从而对全球网络内使用的耗材进行监督。＂
　　＂The suggested strategy focuses on standardization of equipment, standardization of single-use assemblies by definition of standard components, and design rules for consumables,＂ they point out. ＂We also recommend the introduction of a common approach for the qualification of single-use assemblies within a company and the development and companywide introduction of tools, which provide global oversight on consumables in use within a network.＂
　　原文链接：
　　https://www.genengnews.com/topics/bioprocessing/strategic-tech-sourcing-key-to-avoiding-supplier-dependency/
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